Pokémon Stratus takes place in the Wako Region. The Wako Region holds long traditions of being in tune to nature and the environment. Professor Sequoia, the acting Pokémon Professor of Wako, is also a renowned ecologist. Through her work on Pokémon ecosystems, she has uncovered some curious changes lately. As she notes in her most recent update, "The whispering wind has become a strong gale...I can feel its anger." She needs your help to uncover what is happening to the beloved nature of Wako! Something about the alterations is not right, and seems to be the work of something evil...Will you be the hero to save the region and restore balance?